DNA is Obscured by Closed Chromatin (IMAGE) American Institute of Physics Caption DNA is obscured by closed chromatin, an innately protective structure made up of proteins that interact with each other and with DNA. New activation associated proteins (AAPs) can be custom-built to bind near and open up chromatin so that DNA is made more accessible to gene-editing molecules like CRISPR. Credit Illustration by Karmella Haynes Usage Restrictions Journalists may use this image only with appropriate credit. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.