Regulatory T cells engineered with TCR signaling-responsive IL-2 nanogels suppress alloimmunity in sites of antigen encounter (IMAGE)

American Association for the Advancement of Science (AAAS)

Regulatory T cells engineered with TCR signaling-responsive IL-2 nanogels suppress alloimmunity in sites of antigen encounter

Caption

Cartoon describing the application of our engineered regulatory T cells in transplantation and autoimmunity. This material relates to a paper that appeared in the Nov. 11, 2020, issue of Science Translational Medicine, published by AAAS. The paper, by S.K. Eskandari at Harvard Medical School in Boston, MA; and colleagues was titled, "Regulatory T cells engineered with TCR signaling-responsive IL-2 nanogels suppress alloimmunity in sites of antigen encounter."

Credit

[Credit: Eskandari <i>et al</i>.]

Usage Restrictions

Please cite the owner of the material when publishing. This material may be freely used by reporters as part of news coverage, with proper attribution. Non-reporters must contact <i>Science</i> for permission.

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.