PINK1-Parkinson (IMAGE)
Caption
The PINK1 gene plays a role in Parkinson's disease. If the gene is switched off in the fly, the mitochondria (green) are damaged and the animal's muscle fibres (red) disintegrate. The activation of the Ret receptor, which binds the growth factor GNDF in humans, counteracts this degeneration.
Credit
MPI of Neurobiology / Klein
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