The crystal structure of the N-terminal RNA-binding domain of SARS-CoV-2 nucleocapsid protein (IMAGE)

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The crystal structure of the N-terminal RNA-binding domain of SARS-CoV-2 nucleocapsid protein

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The crystal structure of the N-terminal RNA-binding domain of SARS-CoV-2 nucleocapsid protein was determined by X-ray. Compared with other previously reported coronavirus nucleocapsid protein N-terminal domains, the authors have identified a unique potential RNA-binding pocket that can guide the design of novel antiviral drugs targeting SARS-CoV-2.

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Acta Pharmaceutica Sinica B

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