Merkel Cell Polyomavirus Positive Merkel Cell Carcinoma (IMAGE)

National Centre for Biological Sciences

Merkel Cell Polyomavirus Positive Merkel Cell Carcinoma

Caption

Seven cases of Merkel cell carcinoma were found positive for Merkel cell polyomavirus. H&E staining shows epidermis with a tumor below composed of malignant round cells, medium power. Tumor cells show MCV Large T antigen positivity ranging from strong positivity (cases #2, #4, #7, #17 and #18) to weak/focal positivity (cases #12 and #13). Image for Cases #18 is of CM2B4 staining, as it was not tested with Ab3.

Credit

Reety Arora, Bharat Rekhi, Pratik Chandrani, Sudhir Krishna, Amit Dutt

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