SARS-CoV-2 spike Y453F & L452R variants (IMAGE) Kumamoto University Caption SARS-CoV-2 Y453F and L452R variants contribute to evasion from cellular immunity and the L452R variant also increases viral infectivity. Credit Dr. Chihiro Motozono Usage Restrictions <p>Graphical abstract from <a href="https://www.sciencedirect.com/science/article/pii/S1931312821002845"> Motozono, C. et.al., Cell Host & Microbe, 2021</a>. </p> <p>This image is made available under the terms of <a href="https://creativecommons.org/licenses/by/4.0/">CC by 4.0</a>. Any further distribution of this work must follow the terms of this license. </p> License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.