Lung Stroma Respond to Gut Microbe Signals (IMAGE)

Cell Press

Lung Stroma Respond to Gut Microbe Signals

Caption

This visual depicts the findings of Bradley and Finsterbusch et al. who identify lung stroma as the target of microbiota-driven signals that set the interferon signature in these cells. Antibiotic treatment reduces gut microbiota and the lung stromal interferon signature and facilitates early influenza virus replication in lung epithelia, effects that can be reversed by fecal transplantation.

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Bradley and Finsterbusch et al./<i>Cell Reports</i>

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