Protein PylB Catalyzes Formation of 3-methyl-ornithine (IMAGE)
Caption
On the way to the production of pyrrolysine, an exotic amino acid occurring in only a few exotic organisms, the conversion of lysine to methylornithine is the decisive step. Scientists at the Technische Universitaet Muenchen succeeded in crystallizing the enzyme PylB which is responsible for this transformation and elucidated its structure. Top of the image: reactive center with an iron-sulfur cluster (red / yellow), the cofactor S-adenosylmethionine (SAM), and in the center of the image the product: 3-methyl-ornithine (3MO)
Credit
Image: Felix Quitterer, TU Muenchen
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