GBps Proteins Kill Bacteria With Antimicrobial Sacs (3 of 4) (IMAGE)

American Association for the Advancement of Science (AAAS)

GBps Proteins Kill Bacteria With Antimicrobial Sacs (3 of 4)

Caption

Fluorescent micrograph of a 65kDa GTPase, Gbp1 (green), that belongs to a family of immune GTPases needed to protect the host from bacterial infection. Here Gbp1 targets mycobacteria (magenta rods) in IFN-γ-activated macrophages (red, actin staining; blue, DAPI nuclear staining) to help eliminate the microbe. Original magnification, 100x. This image relates to an article that appeared in the May 6, 2011, issue of Science, published by AAAS. The study, by Bae-Hoon Kim of Yale University School of Medicine in New Haven, Conn., and colleagues, was titled, "A Family of IFN-Gamma–Inducible 65-kD GTPases Protects Against Bacterial Infection."

Credit

[Image courtesy of John MacMicking]

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