Peptide (IMAGE)

University of Illinois Grainger College of Engineering

Peptide

Caption

In this image the grey crosses are peptides scanned projected into a 2-D plane spanned by the sequence distance to a known antimicrobial peptide (x-axis) and prediction confidence of the classifier that the peptide is membrane active (y-axis). We detect membrane activity in diverse classes of peptides including neuropeptides, topogenic peptides, and viral fusion proteins. Membrane activity is mediated through the induction if negative Guassian curvature in the membrane (inset).

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University of Illinois

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