Biased Signaling as a Weapon Against Drug Tolerance (IMAGE)

American Association for the Advancement of Science (AAAS)

Biased Signaling as a Weapon Against Drug Tolerance

Caption

Microscopy analysis showed the X4-2-6 peptide did not alter the colocalization of the CXCR4 receptor with beta-arrestin 2 (BA2) in an immortal T cell line. This material relates to a paper that appeared in the Oct. 16, 2018, issue of Science Signaling, published by AAAS. The paper, by author at institution in location; and colleagues was titled, "Biased antagonism of CXCR4 avoids antagonist tolerance."

Credit

B. Hitchinson<i> et al., Science Signaling </i>(2018)

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