Comparing Strains of Lab Mice Reveals Mutations (9 of 9) (IMAGE)

American Association for the Advancement of Science (AAAS)

Comparing Strains of Lab Mice Reveals Mutations (9 of 9)

Caption

Can you tell the difference? C57BL/6J (right) and C57BL/6N (left) mice look the same on the outside, but are different on the inside. A gene mutation in C57BL/6N mice that occurred between 1961 and 1974 affects the response of these mice to the drug, cocaine, and reveals a new gene pathway in the response to these psychoactive drugs. This image relates to a paper that appeared in the 20 Dec., 2013, issue of Science, published by AAAS. The paper, by Vivek Kumar at University of Texas Southwestern Medical Center in Dallas, Texas, and colleagues was titled, "C57BL/6N Mutation in Cytoplasmic FMR interacting protein 2 Regulates Cocaine Response."

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[Image courtesy of The Jackson Laboratory]

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