Development of the Hemodynamic Response (IMAGE) Columbia University Caption Left shows representative gray-scale MS-OISI images of the cortical surface and difference maps displaying changes in total hemoglobin concentration in response to stimulation for three age groups. Right shows averaged oxygenated, deoxygenated, and total hemoglobin time-courses for each age group. Gray region denotes the stimulation period. Credit Columbia Engineering Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.