Computational and Animal Modeling Guides Clinical Testing of Tissue-Engineered Vascular Grafts (6 of 7) (VIDEO)
Caption
After a biodegradable tissue-engineered vascular graft (white) is connected to a normal blood vessel (red), new tissue forms on the graft, resulting in a narrowing (stenosis). This video represents a reconstruction of intravascular ultrasound (IVUS) data over time, transitioning between data obtained 1 week, 6 weeks, 6 months, and 1 year after graft implantation in lambs. This material relates to a paper that appeared in the Apr. 1, 2020, issue of Science Translational Medicine, published by AAAS. The paper, by J.D. Drews at Nationwide Children's Hospital in Columbus, OH; and colleagues was titled, "Spontaneous reversal of stenosis in tissue-engineered vascular grafts."
Credit
[Credit: Breuer Lab, Nationwide Children's Hospital]
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