Restoring Uptake of an Ion Channel Mitigates Inflammatory Pain in Rats (2 of 2) (IMAGE)

American Association for the Advancement of Science (AAAS)

Restoring Uptake of an Ion Channel Mitigates Inflammatory Pain in Rats (2 of 2)

Caption

The uptake of TRPV1 into human kidney cells depended on colocalization with the protein clathrin (red). This material relates to a paper that appeared in the Jun. 19, 2019, issue of Science Translational Medicine, published by AAAS. The paper, by J. Liu at Peking University Health Science Center in Beijing, China; and colleagues was titled, "CDK5 inhibits the clathrin-dependent internalization of TRPV1 by phosphorylating the clathrin adaptor protein AP2μ2."

Credit

[Credit: J. Liu <i>et al., Science Signaling</i> (2019)]

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