Tau Tangles in a Disease Neuron (IMAGE) Indiana University Caption Indiana University scientists have identified 24 compounds that increase the brain's production of the enzyme NMNAT2, which helps prevent the formation of these tangles associated with neurodegenerative disorders such as Alzheimer's disease. Credit Image courtesy of the National Institute on Aging/National Institutes of Health Usage Restrictions Credit: Image courtesy of the National Institute on Aging/National Institutes of Health License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.