Cells Accumulate BACE1 (IMAGE) Rockefeller University Press Caption A study in the Journal of Cell Biology suggests that sluggish recycling of the BACE1 enzyme could promote Alzheimer's disease. Relative to control cells (left), cells short on the protein VPS35 (right) accumulate more BACE1 (red) in endosomes (green). BACE1 in endosomes appears yellow. Credit Wen, L., et al. 2011. J. Cell Biol. <A HREF="http://dx.doi.org/10.1083/jcb.201105109">http://dx.doi.org/10.1083/jcb.201105109</A> Usage Restrictions Reporters may freely use these materials in news coverage, with the appropriate credit information. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.