B Cell-To-Macrophage Transdifferentiation (IMAGE)

Cell Press

B Cell-To-Macrophage Transdifferentiation

Caption

Stills from time-lapse video showing transdifferentiation of pre-B cells into yeast-eating macrophages. Green fluorescent pre-B cells surrounded by red fluorescent Candida albicans at different hours after activation of C/EBPa (shown are same fields). Note that transdifferentiated macrophages in green aggregate while taking up the yeast, which now appear orange.

Credit

J.L. Sardina and T. Zimmermann

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