Breast Tissue (IMAGE)

Cell Press

Breast Tissue

Caption

This image shows breast sections of a 17 (left) and a 58 year old woman (right) stained for a luminal marker (green) and a myoepithelial/basal marker (red). The luminal cells lose fidelity with age which causes them to appear less luminal and more basal. High-dimensional analysis pinpointed this key age-related change in the luminal population, which may be associated with higher breast cancer risk.

Credit

Jonathan K Lee in the lab of Dr. Mark LaBarge

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