Compound from Sea Sponge May Offer Safer Cancer Drug (1 of 5) (IMAGE)

American Association for the Advancement of Science (AAAS)

Compound from Sea Sponge May Offer Safer Cancer Drug (1 of 5)

Caption

HeLa cells treated with DZ-2384 (center) show the presence of mostly bipolar spindles with stunted microtubules and visibly misaligned chromosomes, while vinorelbine-treated cells (right) lacked any detectable spindle microtubules in both cell lines. Samples were immunostained with an antibody to α-tubulin (green) and phalloidin (red) and with DAPI (blue). Images were acquired by confocal microscopy with a 40x objective. Insets show an enlargement of single cells (bottom).

Credit

Wieczorek <i>et al., Science Translational Medicine</i> (2016)

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