Crawling Paths of Larvae (IMAGE)

University at Buffalo

Crawling Paths of Larvae

Caption

Colored lines show the paths of crawling fruit fly larvae. Larvae with a mutant form of the human huntingtin protein that causes Huntington's disease crawled poorly (center) compared with normal larvae (left). But when larvae carrying the Huntington's disease protein also produced extra quantities of the Rab4 protein, crawling improved, though not completely (right).

Credit

Credit: White, J.A., Krzystek, T.J., Hoffmar-Glennon, H. et al., Acta Neuropathologica Communciations, July 2020. The image is adapted from a graphic in the journal article, which is distributed under Creative Commons Attribution 4.0 International License, https://creativecommons.org/licenses/by/4.0/

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