DMD-iPSCs Derived Skeletal Cells (IMAGE)

Center for iPS Cell Research and Application - Kyoto University

DMD-iPSCs Derived Skeletal Cells

Caption

This image shows immunofluorescence staining of skeletal cells differentiated from DMD-iPS cells. Untreated DMD skeletal cells do not express dystrophin (green) due to the deletion of exon 44. However, after any of the three correction strategies are applied to iPS cells, differentiation into skeletal cells results in normal dystrophin expression. Scale bar, 50 μm.

Credit

Dr. Akitsu Hotta, Kyoto University

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