Cells Fuse (IMAGE)

UT Southwestern Medical Center

Cells Fuse

Caption

Multiple actin filaments (magenta) are organized around a dynamin helical polymer (rainbow colored) in this model derived from cryo-electron tomography. Recent UTSW research shows that by bundling F-actin, dynamin increases the mechanical strength of the actin cytoskeleton and enables the formation of invasive membrane protrusions during cell-cell fusion. This unique multifilament bundling mechanism may be generally applicable to other cytoskeletal remodeling events involving dynamin and actin.

Credit

UTSW

Usage Restrictions

None

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.