CRF neurons (IMAGE)

Nagoya University

CRF neurons

Caption

The optogenetic tool "Channelrhodopsin2" expresses CRF neurons in the paraventricular nucleus of the hypothalamus in mice. These neurons were found to be part of the neural pathway that is crucial for the circadian regulation of sleep and wakefulness. Overactivity of CRF neurons due to stress or disturbed circadian rhythm is likely to cause insomnia and other sleep disorders in humans.

Credit

Daisuke Ono

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