The Dichotomy of Androgen Action in the Gut and Its Ink in Colorecta Cancer (IMAGE)

International Society for Stem Cell Research

The Dichotomy of Androgen Action in the Gut and Its Ink in Colorecta Cancer

Caption

A higher incidence of colorectal cancer has been seen in males. In this issue of Stem Cell Reports, Yu et al. discovered the role of androgen in proliferation and differentiation of intestinal stem cells, a mechanism that may explain the higher levels of colorectal cancer in males. The dichotomy of androgen action in the gut and its ink in colorectal cancer is illustrated by the yin-yang symbol divided the cross section of intestine into male part (black zone with structure formula of testosterone) and female part (white zone with formula of estrogen).

Credit

Yu et al

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Must be credited to the published research in Stem Cell Reports and to the researchers.

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