Classification Scheme Developed for Newly Identified Multiple Sclerosis-like Disease (IMAGE)

Tohoku University

Classification Scheme Developed for Newly Identified Multiple Sclerosis-like Disease

Caption

(1) Astrocyte lysis: extensive loss of astrocytes with fragmented and/or dust-like particles; (2) progenitor recruitment: loss of astrocytes except small nucleated cells with GFAP-positive fibre-forming foot processes; (3) protoplasmic gliosis: presence of star-shaped astrocytes with abundant GFAP-reactive cytoplasm; and (4) fibrous gliosis: lesions composed of densely packed mature astrocytes.

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Tohoku University

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Tohoku University

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