Cell Proliferation in Hard Environments (1 of 3) (IMAGE)

American Association for the Advancement of Science (AAAS)

Cell Proliferation in Hard Environments (1 of 3)

Caption

Cas phosphorylation is reduced in the vascular smooth muscle cells of Rac-null arteries. CaspY410 staining of injured femoral artery sections from Rac1fl/fl;SM-iCre mice treated with vehicle. This image relates to a paper that appeared in the June 17, 2014, issue of Science Signaling, published by AAAS. The paper, by Dr. Y.H. Bae at the University of Pennsylvania in Philadelphia, Pa., and colleagues was titled, "A FAK-Cas-Rac-Lamellipodin Signaling Module Transduces Extracellular Matrix Stiffness into Mechanosensitive Cell Cycling."

Credit

Keeley L. Mui

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