Ebola Virus Persistence (IMAGE)

US Army Medical Research Institute of Infectious Diseases

Ebola Virus Persistence

Caption

Red dots in the eye diagram indicate the cells with Ebola virus persistence in the vitreous humor and its immediately adjacent tissue of survivor eyes. Ebola virus genomic RNA in situ hybridization signal (red chromogen) was detected in a hematoxylin counterstained (blue in circle) eye section of rhesus monkey survivor. Fluorescent detection of Ebola virus replicative intermediate RNA (green fluorescence, red fluorescence is Ebola virus genomic RNA) by confocal microscope suggests Ebola virus replicates in the immune privileged sites.

Credit

Xiankun Zeng and William Discher, U.S. Army Medical Research Institute of Infectious Diseases

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