Lignin Globules (IMAGE) University of California - Riverside Caption Co-solvents THF and water cause lignin to dissociate from itself and cellulose, expanding into a random coil. Credit Charles Cai/UCR Usage Restrictions With credit to: Charles Cai/UCR License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.