Long Pentraxin 3 (PTX3) Protects Endothelial Cells from Extracellular Histone Cytotoxicity (IMAGE)

University of Tokyo

Long Pentraxin 3 (PTX3) Protects Endothelial Cells from Extracellular Histone Cytotoxicity

Caption

In severe sepsis, extracellular histones originate from a large number of neutrophil extracellular traps (NETs, extracellular fiber networks that snare pathogens and are mostly comprised of DNA from white blood cells), or various damaged cells.

Credit

© 2014 Takao Hamakubo.

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