New Clues to Lupus Development (1 of 3) (IMAGE)

American Association for the Advancement of Science (AAAS)

New Clues to Lupus Development (1 of 3)

Caption

Hematoxylin and eosin stained kidney section from a Nox2-sufficient lupus prone mouse. Glomeruli are hypercellular and show clinical evidence of disease, but are much less severely affected than Nox2 deficient kidneys (see accompanying image). This brightfield image was taken by Allison Campbell on a wide-field microscope (Nikon Eclipse Ti) and a charge-coupled device (CCD) camera (QImaging Retiga 2000R) with NIS Elements software. This image relates to a paper that appeared in the October 24, 2012, issue of Science Translational Medicine, published by AAAS. The paper, by A.M. Campbell at Yale School of Medicine in New Haven, Conn., and colleagues was titled, “NADPH Oxidase Inhibits the Pathogenesis of Systemic Lupus Erythematosus.”

Credit

Credit: Allison Campbell in the lab of Mark Shlomchik

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