Working Mouse Eggs Made From Stem Cells (3 of 4) (IMAGE)

American Association for the Advancement of Science (AAAS)

Working Mouse Eggs Made From Stem Cells (3 of 4)

Caption

(Upper left) This is a merged image of bright field and CFP fluorescence of the isolated reconstituted ovary. (Upper second left) PGCLC-derived GV oocytes and endogenous recipient GV oocytes. (Upper second right) This is a merged image of bright field and CFP fluorescence of the isolated GV oocytes. (Upper right) PGCLC-derived MII oocytes that were maturated in vitro. (Bottom left) PGCLC-derived offspring with black eyes indicated by black arrows. (Bottom right) female offspring from PGCLC-derived oocytes were fully fertile. This image relates to a paper that appeared in the Oct. 4, 2012, issue of Science Express, published by AAAS. The paper, by Mitinori Saitou at Kyoto University in Kyoto, Japan, and colleagues was titled, "Offspring from Oocytes Derived from in vitro Primordial Germ Cell-like Cells in Mice."

Credit

Courtesy of Katsuhiko Hayashi

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