Impact of Cigarette Smoke Components (IMAGE) The Physiological Society Caption Cigarette smoke components, whether delivered by inhalation or more directly into the circulation, negatively impact the fatigue resistance of skeletal muscle. Credit Dr Leonardo Nogueira Usage Restrictions With credit. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.