Novel tRNA-based Inter-kingdom Interaction (IMAGE) Forsyth Institute Caption A hallmark of periodontal disease is a shift from Gram-positive species dominated healthy microbial community to Gram-negative bacteria dominated disease associated (dysbiotic) community. tsRNAs may represent a mechanism evolved in the host to suppress the growth of Gram-negative bacteria to maintain health. Credit N/A Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.