New Pathway to Treat Heart Failure (IMAGE) Thomas Jefferson University Caption Selective activation of the beta2-adrenergic receptor (Beta2AR) by a beta-arrestin-biased pepducin promotes activation of a beta-arrestin signaling pathway that is cardioprotective. Credit Jeffrey Benovic, Thomas Jefferson University Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.