2 Types of Costs to Hosts Associated with Infections (IMAGE)
Caption
Pathogens can directly damage the host tissues. The immune system of the host reduces the pathogen burden (amount of pathogens in the host) through resistance mechanisms. The immune response can also damage the host tissues. The host can reduce costs through tolerance mechanisms that reduce both the direct damage by pathogens and immunopathology (the negative impact of immune system defenses).
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(Credit: Science/AAAS)
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