HIV Tat Feedback Resistor (IMAGE) PLOS Caption HIV Tat transactivates its own expression, but this requires conv ersion from deacetylated Tat (TatD) to acetylated Tat (TatA), a reaction that establishes a feedback resistor and allows the circuit to shut off. Credit Image: Weinberger et al. Usage Restrictions Please cite the authors and PLoS Biology as the source. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.