Unlocking the Full Potential of Conjugate Vaccines (1 of 1) (IMAGE)

American Association for the Advancement of Science (AAAS)

Unlocking the Full Potential of Conjugate Vaccines (1 of 1)

Caption

Some proposed interactions to explain how glycoconjugate vaccines activate an immune response. FDC refers to follicular dendritic cells, which present the conjugate to B cells and T cells. The last two proposals feature a high concentration of antibodies (pink structures). This material relates to a paper that appeared in the Sep. 5, 2018, issue of Science Translational Medicine, published by AAAS. The paper, by R. Rappuoli at GlaxoSmithKline in Siena, Italy; and colleagues was titled, " Glycoconjugate vaccines: Principles and mechanisms."

Credit

R. Rappuoli <i>et al., Science Translational Medicine</i> (2018)

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