Platelets and tvessels (IMAGE)

Uppsala University

Platelets and tvessels

Caption

The image shows platelets (red) in close contact with tumour vessels (green). Platelets are activated in the tumour microenvironment and secrete a large number of growth factors. Conditional knockout of PDGFB in platelets demonstrates its previously unknown role in pericyte recruitment, maintenance of tumour vascular integrity and host protection against metastasis.

Credit

Yanyu Zhang

Usage Restrictions

To accompany coverage of Yanyu Zhang's research.

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