Actin and Poly-UB (IMAGE)

Rice University

Actin and Poly-UB

Caption

In microscopic images of muscle tissue from normal fruit flies (left), fluorescent tags reveal uniform levels of the structural protein actin (blue) and almost no poly-UB, a protein aggregate that is broken apart and recycled by healthy cells. In muscle tissue from flies lacking HSP gene activity (right), actin levels are reduced and cells contain a toxic buildup of poly-UB.

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James McNew/Rice University

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