Screening Mammography Could Benefit Men at High Risk of Breast Cancer (IMAGE)
Caption
Images in a 53-year-old man with Ashkenazi Jewish ancestry with BARD1 genetic mutation and strong family history of breast cancer including male breast cancer in father and premenopausal breast cancer in multiple sisters. Patient was found to have left breast cancer on (a-c) baseline screening mammogram and contralateral right breast cancer on (d-f) subsequent-year screening mammogram. Grouped coarse heterogeneous calcifications in left breast on baseline screening mammogram as shown on magnification views in (a) mediolateral and (b) craniocaudal projections (circles) underwent excisional biopsy, with surgical specimens showing (c) inclusion of targeted calcifications. Pathologic result yielded estrogen receptor (ER)-positive, progesterone receptor (PR)-positive, and human epidermal growth factor receptor 2 (HER2)-negative grade 2 invasive and in situ carcinoma, ultimately treated with mastectomy. One year later, grouped and scattered calcifications were seen on right breast screening mammogram as shown on magnification views in (d) mediolateral and (e) craniocaudal projections (arrows), which underwent SAVI Scout radar-localized excisional biopsy with surgical specimens showing (f) inclusion of targeted calcifications. Pathologic result yielded ER-positive and PR-positive grade 2 ductal carcinoma in situ, which subsequently underwent mastectomy.
Credit
Radiological Society of North America
Usage Restrictions
May use with credit.
License
Licensed content