Osteocalcin and Exercise (IMAGE)

Cell Press

Osteocalcin and Exercise

Caption

This visual abstract depicts the findings of Mera et al., who show that the bone-derived hormone osteocalcin is necessary for optimum exercise capacity and that this hormone decreases with aging in mice, monkeys, and humans of both genders. Osteocalcin promotes muscle uptake and utilization of glucose and lipids during exercise and greatly improves the exercise capacity of old mice.

Credit

Mera et al./<i>Cell Metabolism</i> 2016

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