Tumor Antigens Help Explain Varied Reactions to Immunotherapy (4 of 5) (IMAGE)

American Association for the Advancement of Science (AAAS)

Tumor Antigens Help Explain Varied Reactions to Immunotherapy (4 of 5)

Caption

Cancer Research UK scientists have now discovered rare immune cells inside tumors that recognize an evolved tumor's early, shared features. If these cells could be isolated, and artificially multiplied in the lab, they could form a fearsome cancer-fighting force. This material relates to a paper that appeared in the March 3, 2016, online issue of Science, published by AAAS. The paper, by N. McGranahan at The Francis Crick Institute in London, UK, and colleagues was titled, 'Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade.'

Credit

Cancer Research UK, produced by Phospho Biomedical Animation

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