Figure 1. Schematic Image of monSTIM1 Working Mechanism (IMAGE)

Institute for Basic Science

Figure 1. Schematic Image of monSTIM1 Working Mechanism

Caption

Upon blue light illumination, this optogenetic tool opens calcium channels (CRAC channels), so that calcium (Ca2+) can enter inside the cells. It is formed by two parts: CRY2, and STIM1. CRY2 is sensitive to blue light, and STIM1 activates calcium channels. GFP produces green light and is added to allow the researchers to track monSTIM1 location.

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