DNA Melt Plots (IMAGE)

National Institute of Standards and Technology (NIST)

DNA Melt Plots

Caption

Both graphs show measurements of the DNA melt curve, which characterizes the stability of a particular sequence of DNA when subject to heat. Image at left shows that the measurements, even though they are performed on the same DNA sequence, yield different curves due to uncertainties in the measurement process. Image at right shows that when researchers apply the appropriate mathematical transformation, known as an affine transformation, the variations in the DNA melt curves are removed and they all collapse to form the same curve, as desired.

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NIST

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