Biomimetic Nuclear Pore Complexes (IMAGE) Delft University of Technology Caption Artistic rendering of biomimetic nuclear pore complexes where key nuclear pore proteins (blue ‘spaghetti-like’ molecules) are attached to solid-state nanopores (holes in the orange/brown bottom layer). Remarkably, these biomimetic pores exhibit selectivity (the hallmark of naturally occurring nuclear pores), which means that ImpB proteins (purple) do pass the pores, whereas BSA proteins (yellow) do not. The bottom-up nano-engineering approach allows to investigate behavior of nuclear pores outside the complex cellular environment, and might serve as a platform for testing gene and drug delivery into a cell’s nucleus. Credit Image courtesy Cees Dekker lab TU Delft / Tremani Usage Restrictions Free for news articles License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.