Zebrafish Brain (IMAGE)

Technische Universität Dresden

Zebrafish Brain

Caption

The zebrafish brain has an outstanding regenerative ability, which also manifests after neurodegenerative disease-like conditions. Dr. Caghan Kizil and colleagues generated an Alzheimer's disease model in the adult zebrafish brain, and showed that this remarkable aptitude is enabled by a specific neuro-immune crosstalk. This dynamic interplay activates the proliferation of neural stem cells and subsequently triggers the formation of new neurons. The image shows the spatial organization of immune cells (green) and neurons (red) on a cross section of adult zebrafish forebrain (cell nuclei: blue). Image acquired in Kizil Lab, CRTD and DZNE, Helmholtz Association.

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Kizil Lab

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