A Mathematical Model for Curved Epithelia Uncovers a Novel Geometrical Solid (IMAGE)
Caption
a) Scheme representing planar columnar/cubic monolayer epithelia. Cells are simplified as prisms. b) Scheme illustrating a fold in a columnar/cubic monolayer epithelium. Cells adopt the called "bottle 23 shape" that would be simplified as frusta. c) Mathematical model for an epithelial tube. d) Modelling clay figures illustrating two scutoids participating in a transition and two schemes for scutoids solids. Scutoids are characterized by having at least a vertex in a different plane to the two bases and present curved surfaces. e) A dorsal view of a Protaetia speciose beetle of the Cetoniidae family. The white lines highlight the resemblance of its scutum, scutellum and wings with the shape of the scutoids. Illustration from Dr. Nicolas Gompel, with permission. f) Three-dimensional reconstruction of the cells forming a tube. The four-cell motif (green, yellow, blue and red cells) shows an apico-basal cell intercalation. g) Detail of the apico-basal transition, showing how the blue and yellow cells contact in the apical part, but not in the basal part. The figure also shows that scutoids present concave surfaces.
Credit
Luis M. Escudero (Seville University, Spain), Javier Buceta (Lehigh University, USA), Pedro Gomez-Galvez, Pablo Vicente-Munuera and scientists from Andalucian Center of Developmental Biology, and the Severo Ocha Center of Molecular Biology, among others.
Usage Restrictions
None
License
Licensed content