Model of Glycine Transporter 1 (IMAGE)

European Molecular Biology Laboratory

Model of Glycine Transporter 1

Caption

GlyT1 (light blue) is a protein that transports glycine across the cell membrane (grey). To do this, it opens to the outside and inside of the cell alternately. In contrast to other neurotransmitter transporters, it is bound by its inhibitor (orange) from the intracellular side, rather than the extracellular one. The sybody, a synthetic mini-antibody (dark blue), also inhibits GlyT1 by binding to a novel extracellular site.

Credit

Azadeh Shahsavar/DANDRITE

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Please include credits to Azadeh Shahsavar from DANDRITE.

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