LovD9 (IMAGE)

University of California - Los Angeles

LovD9

Caption

This is a representation of the chemical structure of the mutated enzyme LovD9 used to manufacture the cholesterol-reducing drug simvastatin. The structure of the mutated enzyme and why it is effective in producing simvastatin was determined through X-ray crystallography and molecular dynamics simulations at UCLA.

Credit

UCLA/Codexis

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